Data Details
Disease Name idiopathic pulmonary fibrosis
Tissue lung
Database GEO
Data ID GSE156310
Data Type expression
Platform GPL18573
Species homo sapiens
Sample Number 2
PubMed ID 33859634
Title Disparate interferon signaling and shared aberrant basaloid cells in single-cell profiling of idiopathic pulmonary fibrosis and systemic sclerosis-associated interstitial lung disease
Data Description "To reduce batch effects in analyzing multiple samples, all control, IPF, and SSc-ILD samples were combined into 3 objects by disease status using Seurat's IntegrateData function, followed by integration of these 3 objects."
Keyword pulmonary fibrosis mRNA
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Data Details
Disease Name idiopathic pulmonary fibrosis
Tissue lung
Database GEO
Data ID GSE156310
Data Type expression
Platform GPL18573
Species homo sapiens
Sample Number 2
PubMed ID 33859634
Title Disparate interferon signaling and shared aberrant basaloid cells in single-cell profiling of idiopathic pulmonary fibrosis and systemic sclerosis-associated interstitial lung disease
Data Description "To reduce batch effects in analyzing multiple samples, all control, IPF, and SSc-ILD samples were combined into 3 objects by disease status using Seurat's IntegrateData function, followed by integration of these 3 objects. Following clustering and visualization with uniform manifold approximation and projection (UMAP), cell populations were classified using multiple gene markers in the transcriptome. Doublet cells were manually identified and subsequently removed. To better define individual cell types, the myeloid, lymphoid, epithelial, and stromal populations were separately reclustered. Differential gene expression analysis for IPF versus SSc-ILD cells for each cluster was performed using the Wilcoxon rank-sum statistical test."
Keyword pulmonary fibrosis rna
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FDRdb: Fibrosis Disease-associated RNAnome database

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